Description
Product Characteristics: CBARA1, calcium binding atopy-related autoantigen 1, CALC, DKFZp564C246, EFHA3, FLJ12684, OTTHUMP00000019787, ara CALC, atopy related autoantigen, atopy-related autoantigen CALC, calcium-binding atopy-related autoantigen 1
Target Information: This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Mar 2013]